Annual report [Section 13 and 15(d), not S-K Item 405]

Note 2 - Summary of Significant Accounting Policies (Details Textual)

v3.25.1
Note 2 - Summary of Significant Accounting Policies (Details Textual)
12 Months Ended
Dec. 31, 2024
USD ($)
shares
Dec. 31, 2023
USD ($)
shares
Mar. 31, 2024
$ / shares
Nov. 30, 2019
$ / shares
Accounts Receivable, Allowance for Credit Loss $ 0      
Impairment of Long-lived Assets 77,444 $ 0    
Revenue from Contract with Customer, Including Assessed Tax $ 86,032 $ 198,871    
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | shares 1,297,369 1,597,898    
Number of Operating Segments 1      
Pre Funded Warrant [Member]        
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares     $ 0.001 $ 0.001
Development Revenue [Member]        
Revenue from Contract with Customer, Including Assessed Tax $ 86,032 $ 161,483    
Grant [Member]        
Revenue from Contract with Customer, Including Assessed Tax $ 0 $ 37,388    
Patents [Member]        
Finite-Lived Intangible Asset, Useful Life 20 years      
Other Intangible Assets [Member] | Minimum [Member]        
Finite-Lived Intangible Asset, Useful Life 11 years      
Other Intangible Assets [Member] | Maximum [Member]        
Finite-Lived Intangible Asset, Useful Life 17 years