Annual report pursuant to Section 13 and 15(d)

Warrants (Details)

v3.21.1
Warrants (Details) - USD ($)
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Class of Warrant or Right [Line Items]    
Held in abeyance 803,300  
Warrants    
Class of Warrant or Right [Line Items]    
Outstanding at January 1 (in shares) 2,463,063 713,652
Granted 705,688 1,837,421
Exercised (in shares) (589,941)  
Expired (in shares) (625,642) (88,010)
Outstanding at December 31 (in shares) 1,149,868 2,463,063
Outstanding at January 1 (in dollars per share) $ 7.96 $ 26.19
Granted (in per shares) 8.90 $ 2.35
Exercised (in per share) $ 2.39  
Held in abeyance (803,300)  
Held in abeyance (in dollars per share) $ 2.32  
Expired (in per share) $ 24.44 $ 38.70
Outstanding at December 31 (in dollars per share) $ 6.36 $ 7.96
Pre Funded Warrants [Member]    
Class of Warrant or Right [Line Items]    
Outstanding at January 1 (in shares) 868,443  
Granted   868,443
Exercised (in shares) (548,242)  
Outstanding at December 31 (in shares) 320,201 868,443
Outstanding at January 1 (in dollars per share) $ 0.001  
Granted (in per shares)   $ 0.001
Exercised (in per share) 0.001  
Outstanding at December 31 (in dollars per share) $ 0.001 $ 0.001